The American Journal of Clinical Nutrition published in its February 2006 a report containing conclusions of a research team at University of Arizona, related to links between high fiber diets and colorectal adenoma recurrence.

According to team findings, men who prefer a diet rich in fiber have a significantly reduced risk of colorectal adenoma recurrence. The study conclusions suggests that sex differences in response to fiber diets, as no such effect has been seen in women. The research team notes that many evidences in specific literature show that fiber may influence the colon differently, depending on sex.

Although the process by which these differential response happen remains unclear, future researches should include complicated sex analyses as well as further study of the influence of fiber diets on specific colon locations.

To assess the effect of dietary action as a whole and by sex in the pooled group of 3209 subjects a model of logistic regression were used by researchers. No major effect on adenoma recurrence was concluded in the targeted population. However, among men, fiber was linked with a significant reduced risk of recurrence. Among women wasn't observed any significant association.

While the causes for these different reactions regarding sexes are still unknown, the study advanced the supposition that the differences between the sexes regarding colonic location of tumors and polyps could be the answer.